FOLFIRINOX treatment leading to pathologic complete response of a locally advanced pancreatic cancer
نویسندگان
چکیده
منابع مشابه
FOLFIRINOX in Locally Advanced and Metastatic Pancreatic Cancer: A Single Centre Cohort Study
Introduction: FOLFIRINOX is emerging as new standard of care for fit patients with locally advanced pancreatic cancer (LAPC) and metastatic pancreatic cancer (MPC). However, some of the physicians are reluctant to use FOLFIRINOX due to high toxicity rates reported in earlier studies. We reviewed our experience with FOLFIRINOX in LAPC and MPC, focussing on dose adjustments, toxicity and efficacy...
متن کاملPredicting a response to FOLFIRINOX in pancreatic cancer.
Cancer of the pancreas is highly lethal and it is the fourth leading cause of cancer death in the United States (1). The majority of patients with pancreatic cancer have metastatic disease at the time of diagnosis, and the few patients who present with localized disease often develop metastases within two years of their surgery. Recently, the combination regimens of FOLFIRINOX (2) and Gemcitabi...
متن کاملClinical predictive factors of pathologic complete response in locally advanced rectal cancer
BACKGROUND Predictive factors of pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer (LARC) are still not identified. The purpose of this study was to define them. MATERIALS AND METHODS Data from consecutive LARC patients treated between January 2008 and June 2014 at our Institution were included in the analysis. All patients were tr...
متن کاملFOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis.
BACKGROUND 35% of patients with pancreatic cancer have unresectable locally advanced disease at diagnosis. Several studies have examined systemic chemotherapy with FOLFIRINOX (leucovorin and fluorouracil plus irinotecan and oxaliplatin) in patients with locally advanced pancreatic cancer. We aimed to assess the effectiveness of FOLFIRINOX as first-line treatment in this patient population. ME...
متن کاملLocally advanced pancreatic cancer.
Treatment of locally advanced pancreatic cancer is palliative, based on chemotherapy and according to response, chemoradiotherapy can be applied. The authors summarize three abstracts (#LBA146, #256 and #303) presented on the 2013 ASCO Gastrointestinal Cancers Symposium, which were focused on treatment of locally advanced pancreatic cancer. A discussion is presented about the different chemothe...
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ژورنال
عنوان ژورنال: Journal of Gastrointestinal Oncology
سال: 2018
ISSN: 2078-6891,2219-679X
DOI: 10.21037/jgo.2018.01.07